-近年发表的SCI文章(通讯作者)
Qing Yang#, Fengling Feng#, Pingchao Li#, Enxiang Pan, Chunxiu Wu, Yizi He, Fan Zhang, Jin Zhao, Ruiting Li, Liqiang Feng, Fengyu Hu, Linghua Li, Huachun Zou, Weiping Cai, Thomas Lehner,* Caijun Sun,* and Ling Chen*.Arsenic Trioxide Impacts Viral Latency and Delays Viral Rebound after Termination of ART in Chronically SIV-Infected Macaques. Advanced Science, 2019. 1900319:10.
Xuefeng Niu, Lingzhai Zhao, Linbing Qu, Zhipeng Yao, Fan Zhang, Qihong Yan, Shengnan Zhang, Renshan Liang, Peihai Chen, Jia Luo, Wei Xu, Huibin Lv, Xinglong Liu,Hui Lei, Changhua Yi, Pingchao Li, Qian Wang, Yang Wang, Lei Yu, Xiaoyan Zhang, L. Aubrey Bryan, Edgar Davidson, j. Benjamin Doranz, Liqiang Feng, Weiqi Pan, Fuchun Zhang & Ling Chen (2019) Convalescent patient-derived monoclonal antibodies targeting different epitopes of E protein confer protection against Zika virus in a neonatal mouse model, Emerging Microbes & Infections, 8:1, 749-759, DOI: 10.1080/22221751.2019.1614885.
Feng F, Zhao J, Li P, Li R, Chen L, Sun C. Preexisting Virus-Specific T Lymphocytes-Mediated Enhancement of Adenovirus Infections to Human Blood CD14+ Cells. Viruses. 2019;11(2):154. Published 2019 Feb 13. doi:10.3390 711020154.
Xinli Zhang,Linbing Qu,Ling Chen,Chen Chen.Improvement of cardiomyocyte function by in vivo hexarelin treatment in streptozotocin-induced diabetic rats.Physiol Rep. 2018 Feb;6(4). doi: 10.14814/phy2.13612.
Pingchao Li,Fengling Feng,Enxiang Pan, Xiaozhen Fan,Qing Yang,Min Guan,Ling Chen,Caijun Sun.Scavenger receptor-mediated Ad5 entry and acLDL accumulation in monocytes/macrophages synergistically trigger innate responses against viral infection.Virology. 2018 Jun;519:86-98. doi: 10.1016/j.virol.2018.04.005. Epub 2018 Apr 19.
Ying Feng,Xikui Sun,Xianmiao Ye,Yupeng Feng,Jinlin Wang,Xuehua Zheng,Xinglong Liu,Changhua Yi,Mingli Hao,Qian Wang,Feng Li,Wei Xu,Liang Li,Chufang Li,Rong Zhou,Ling Chen,Liqiang Feng.Hexon and fiber of adenovirus type 14 and 55 are major targets of neutralizing antibody but only fiber-specific antibody contributes to cross-neutralizing activity.Virology. 2018 May;518:272-283. doi: 10.1016/j.virol.2018.03.002. Epub 2018 Mar 15.
Weiqi Pan,Haojun Xie,Xiaobo Li,Wenda Guan,Peihai Chen,Beiwu Zhang,Mincong Zhang,Ji Dong,Qian Wang,Zhixia Li,Shufen Li,Zifeng Yang,Chufang Li,Nanshan Zhong,Jicheng Huang,Ling Chen.Patient-derived avian influenza A (H5N6) virus is highly pathogenic in mice but can be effectively treated by anti-influenza polyclonal antibodies.Emerg Microbes Infect. 2018 Jun 13;7(1):107. doi: 10.1038/s41426-018-0113-2.
Yupeng Feng,Chufang Li,Peiyu Hu,Qian Wang,Xuehua Zheng,Yongkun Zhao,Yi Shi,Songtao Yang,Changhua Yi,Ying Feng,ChunxiuWu,Linbing Qu,WeiXu,YaoLi,CaijunSun,FuGerogeGao,XianzhuXia,Liqiang Feng,Ling Chen.An adenovirus serotype 2-vectored ebolavirus vaccine generates robust antibody and cell-mediated immune responses in mice and rhesus macaques.Emerg Microbes Infect. 2018 Jun 6;7(1):101. doi: 10.1038/s41426-018-0102-5.
Pan E, Feng F, Li P, Yang Q, Ma X, Wu C, Zhao J, Yan H, Chen R, Chen L, Sun C. Immune Protection of SIV Challenge by PD-1 Blockade During Vaccination in Rhesus Monkeys. Front Immunol. 2018 Oct 23;9:2415
Tongjin Wu, Feng Ma, Xiuchang Ma, Weizhe Jia, Pan Enxiang, Genhong Cheng, Ling Chen,Caijun Sun. Regulating innate and adaptive immunity for controlling SIV infection by25-hydroxycholesterol. Front. Immunol. 2018 Nov 21;9:2686
X Liu, L Qu, X Ye, C Yi, X Zheng, M Hao, W Su, Z Yao, P Chen, S Zhang, Y Feng, Q Wang, Q Yan, P Li, H Li, L Feng and L. Chen, ' Incorporation of NS1 and prM/M are important to confer effective protection of adenovirus-vectored Zika virus vaccine carrying E protein', npj Vaccines, 29 (2018).
Y Feng, C Li, P Hu, Q Wang, X Zheng, Y Zhao, Y Shi, S Yang, C Yi, Y Feng, C Wu, L Qu, W Xu, Y Li, C Sun, F Gao, X Xia, L Feng and L. Chen, ' An adenovirus serotype 2 vectored ebolavirus vaccine generates robust antibody and cell-mediated immune responses in mice and rhesus macaques', Emerg Microbes Infect, doi:10.1038/s41426-018-0102-5
F. Li, P. R. Wang, L. B. Qu, C. H. Yi, F. C. Zhang, X. P. Tang, L. G. Zhang, and L. Chen, ' Scavenger receptor-mediated Ad5 entry and acLDL accumulation in monocytes/macrophages synergistically trigger innate responses against viral infection', Virology, Apr 19;519:86-98.
P Li, F Feng, E Pan, X Fan, Q Yang, M Guan, L Chen*, C Sun*, 'Axl Is Not Essential for Zika Virus Infection in the Mouse Brain', Emerg Microbes Infect, 6 (2017), e16.
Feng Y, Sun X, Ye X, Feng Y, Wang J, Zheng X, Liu X, Yi C, Hao M, Wang Q, Li F, Xu W5, Li L, Li C, Zhou R, Chen L, Feng L., ' Hexon and fiber of adenovirus type 14 and 55 are major targets of neutralizing antibody but only fiber-specific antibody contributes to cross-neutralizing activity.', Virology, 2018. Mar 15;518:272-283.
Zhang Y, Feng Y, Li L, Ye X, Wang J, Wang Q, Li P, Li N, Zheng X, Gao X, Li C, Li F, Sun B, Lai K, Su Z, Zhong N, Chen L, Feng L., ' Immunization with an adenovirus-vectored TB vaccine containing Ag85A-Mtb32 effectively alleviates allergic asthma.', JOURNAL OF MOLECULAR MEDICINE-JMM, 2018, Apr;96(3-4):249-263.
Xie H, Li C, Zhang M, Zhong N, Chen L. ' Association between IRGM polymorphisms and tuberculosis risk: A meta-analysis.', Medicine (Baltimore). ,2017. Oct;96(43):e8189.
Yang, Q ; Ding, YY ; Feng, FL ; Pan, EX; Fan, XZ; Ma, XC ; Chen, L ; Zhao, JL; Sun, CJ ' "Structure-optimized dihydropyranoindole derivative GIBH-LRA002 potentially reactivated viral latency in primary CD4+ T lymphocytes of chronic HIV-1 patients".', MEDCHEMCOMM, 2017, 8(9): 1806-1809.
F. Li, P. R. Wang, L. B. Qu, C. H. Yi, F. C. Zhang, X. P. Tang, L. G. Zhang, and L. Chen, 'Axl Is Not Essential for Zika Virus Infection in the Mouse Brain', Emerg Microbes Infect, 6 (2017), e16.
X. Zheng, X. Rong, Y. Feng, X. Sun, L. Li, Q. Wang, M. Wang, W. Liu, C. Li, Y. Yang, R. Zhou, J. Lu, L. Feng, and L. Chen, 'Seroprevalence of Neutralizing Antibodies against Adenovirus Type 14 and 55 in Healthy Adults in Southern China', Emerg Microbes Infect, 6 (2017), e43.
Q. Zhang, M. Gui, X. Niu, S. He, R. Wang, Y. Feng, A. Kroeker, Y. Zuo, H. Wang, Y. Wang, J. Li, C. Li, Y. Shi, X. Shi, G. F. Gao, Y. Xiang, X. Qiu, L. Chen, and L. Zhang, 'Potent Neutralizing Monoclonal Antibodies against Ebola Virus Infection', Sci Rep, 6 (2016), 25856.
X. Wang, C. Sun, P. Li, T. Wu, H. Zhou, D. Yang, Y. Liu, X. Ma, Z. Song, Q. Nian, L. Feng, C. Qin, L. Chen, and R. Tang, 'Vaccine Engineering with Dual-Functional Mineral Shell: A Promising Strategy to Overcome Preexisting Immunity', Adv Mater, 28 (2016), 694-700.
Y. Ren, C. Li, L. Feng, W. Pan, L. Li, Q. Wang, J. Li, N. Li, L. Han, X. Zheng, X. Niu, C. Sun, and L. Chen, 'Proton Channel Activity of Influenza a Virus Matrix Protein 2 Contributes to Autophagy Arrest', J Virol, 90 (2015), 591-8.
H. Zhi, L. Qu, F. Wu, L. Chen, and J. Tao, 'Group Iie Secretory Phospholipase A2 Regulates Lipolysis in Adipocytes', Obesity (Silver Spring), 23 (2015), 760-8.
Y. Zhang, L. Feng, L. Li, D. Wang, C. Li, C. Sun, P. Li, X. Zheng, Y. Liu, W. Yang, X. Niu, N. Zhong, and L. Chen, 'Effects of the Fusion Design and Immunization Route on the Immunogenicity of Ag85a-Mtb32 in Adenoviral Vectored Tuberculosis Vaccine', Hum Vaccin Immunother, 11 (2015), 1803-13.
W. Pan, L. Han, Z. Dong, X. Niu, Z. Li, L. Bao, C. Li, Q. Luo, Z. Yang, X. Li, J. Huang, L. Feng, C. Qin, N. Zhong, and L. Chen, 'Induction of Neutralizing Antibodies to Influenza a Virus H7n9 by Inactivated Whole Virus in Mice and Nonhuman Primates', Antiviral Res, 107 (2014), 1-5.
W. Pan, Z. Dong, F. Li, W. Meng, L. Feng, X. Niu, C. Li, Q. Luo, Z. Li, C. Sun, and L. Chen, 'Visualizing Influenza Virus Infection in Living Mice', Nat Commun, 4 (2013), 2369.
W. Meng, W. Pan, A. J. Zhang, Z. Li, G. Wei, L. Feng, Z. Dong, C. Li, X. Hu, C. Sun, Q. Luo, K. Y. Yuen, N. Zhong, and L. Chen, 'Rapid Generation of Human-Like Neutralizing Monoclonal Antibodies in Urgent Preparedness for Influenza Pandemics and Virulent Infectious Diseases', PLoS One, 8 (2013), e66276.
Lijun Xiao, Dimin Wang, Caijun Sun, Pingchao Li, Yi Jin, Liqiang Feng, and Ling Chen, 'Enhancement of Siv-Specific Cell Mediated Immune Responses by Co-Administration of Soluble Pd-1 and Tim-3 as Molecular Adjuvants in Mice', Human Vaccines & Immunotherapeutics, 10 (2013), 724-33.
Y. Zhang, C. Sun, L. Feng, L. Xiao, and L. Chen, 'Enhancement of Gag-Specific but Reduction of Env- and Pol-Specific Cd8+ T Cell Responses by Simian Immunodeficiency Virus Nonstructural Proteins in Mice', AIDS Res Hum Retroviruses, 28 (2012), 374-83.
W. Pan, Z. Dong, W. Meng, W. Zhang, T. Li, C. Li, B. Zhang, and L. Chen, 'Improvement of Influenza Vaccine Strain a/Vietnam/1194/2004 (H5n1) Growth with the Neuraminidase Packaging Sequence from a/Puerto Rico/8/34', Hum Vaccin Immunother, 8 (2012), 252-9.
C. Sun, L. Feng, Y. Zhang, L. Xiao, W. Pan, C. Li, L. Zhang, and L. Chen, 'Circumventing Antivector Immunity by Using Adenovirus-Infected Blood Cells for Repeated Application of Adenovirus-Vectored Vaccines: Proof of Concept in Rhesus Macaques', J Virol, 86 (2012), 11031-42.
M. Guan, L. Qu, W. Tan, L. Chen, and C. W. Wong, 'Hepatocyte Nuclear Factor-4 Alpha Regulates Liver Triglyceride Metabolism in Part through Secreted Phospholipase a(2) Gxiib', Hepatology, 53 (2011), 458-66.
X. Hu, W. Meng, Z. Dong, W. Pan, C. Sun, and L. Chen, 'Comparative Immunogenicity of Recombinant Adenovirus-Vectored Vaccines Expressing Different Forms of Hemagglutinin (Ha) Proteins from the H5 Serotype of Influenza a Viruses in Mice', Virus Res, 155 (2011), 156-62.
C. Sun, Y. Zhang, L. Feng, W. Pan, M. Zhang, Z. Hong, X. Ma, X. Chen, and L. Chen, 'Epidemiology of Adenovirus Type 5 Neutralizing Antibodies in Healthy People and Aids Patients in Guangzhou, Southern China', Vaccine, 29 (2011), 3837-41.
C. Sun, Y. Zhang, Y. Liu, M. Zhang, and L. Chen, 'Short Communication: Enhancement of Immunogenicity of Replication-Defective Adenovirus-Based Human Immunodeficiency Virus Vaccines in Rhesus Monkeys', AIDS Res Hum Retroviruses, 27 (2011), 681-6.
W. Hu, S. Zeng, C. Li, Y. Jie, Z. Li, and L. Chen, 'Identification of Hits as Matrix-2 Protein Inhibitors through the Focused Screening of a Small Primary Amine Library', J Med Chem, 53 (2010), 3831-4.
F. Li, L. Feng, W. Pan, Z. Dong, C. Li, C. Sun, and L. Chen, 'Generation of Replication-Competent Recombinant Influenza a Viruses Carrying a Reporter Gene Harbored in the Neuraminidase Segment', J Virol, 84 (2010), 12075-81.
G. Wei, W. Meng, H. Guo, W. Pan, J. Liu, T. Peng, L. Chen, and C. Y. Chen, 'Potent Neutralization of Influenza a Virus by a Single-Domain Antibody Blocking M2 Ion Channel Protein', PLoS One, 6 (2011), e28309.
M. Zhong, X. Ma, C. Sun, and L. Chen, 'Micrornas Reduce Tumor Growth and Contribute to Enhance Cytotoxicity Induced by Gefitinib in Non-Small Cell Lung Cancer', Chem Biol Interact, 184 (2010), 431-8.